About this event
Chromatin regulators often require multiple binding events, involving DNA, the nucleosome core, histone post-translational modifications (PTMs) and other protein / nucleic acid elements: a concept known as multivalency. Dissecting this complexity demands highly defined, physiologically relevant experimental strategies. To this end we have pioneered access to fully defined nucleosomes and use these tools to functionally dissect chromatin factors and yield maximal insight from genomic mapping. Our studies highlight the importance of an unbiased interrogation of chromatin mechanisms at the nucleosomal level where multiple elements of the 'histone code' are revealed.
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Dr. Keogh earned his PhD from Imperial College London and completed postdoctoral studies in London and at Harvard Medical School. His research has focused on technology development, genetic networks, and chromatin function / epigenetic regulation.
Ellen is an expert in chromatin biology. She earned her PhD from the University of Pennsylvania and completed postdoctoral studies at the Jackson Laboratory for Genomic Medicine. At EpiCypher, Ellen leads scientific content and technical communications for products, services, and their applications.
EpiCypher is a world-leading provider of innovative research solutions to advance chromatin biology and improve human health. Take your project to the next level with EpiCypher's CUTANA™ CUT&RUN/CUT&Tag chromatin profiling assays and comprehensive class of nucleosome substrates and enzymes.
