About this event
Wednesday March 24th, 2021 - 3pm GMT / 4pm CET / 11am EDT
Duration: 30 minutes
Chromatin exists as a non-linear, “three-dimensional” structure in the nuclear space, and refers to the complex of DNA and proteins and how they are packaged within a cell. This high level of organisation puts another layer of regulation and control on an already complicated system.
Epigenetics can refer to DNA methylation, histone modifications, non-coding RNA, and Chromosome Conformation Signatures (CCSs), which is the highest framework level of epigenetic regulation. These signatures can be used to identify disease states and for clinical diagnostics.
Using two studies developed with pharma partners, this presentation from Ewan Hunter (Chief Data Officer, Oxford Biodynamics) describes the EpiSwitch technology and how it was utilised to develop a liquid biopsy for diffuse large B-cell lymphoma (DLBCL) prognosis whilst conforming to digital PCR gold standards.
This webinar has been made possible with the kind support of our partner, Agilent.
Front Line Genomics is a genomics-focused media company, with a social mission to deliver the benefits of genomics to patients faster. We organise the Festival of Genomics, digital events and webinars. We also produce reports and operate a content-rich website.
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