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Liquid Biopsy ONLINE - Webinar 4: Novel biomarkers and other fluids

About this event

One of the most exciting applications of cancer genomics is the development of liquid biopsies. Measuring circulating tumour cells or cell-free DNA in bodily fluid, liquid biopsies can be used to detect cancer, monitor treatment response and help map tumour evolution. Arming the clinician with in-depth molecular information in a non-invasive manner can influence clinical decision making, thus immense efforts are underway to develop reliable liquid biopsy assays.

However, challenges remain. Detecting tumour material in the sample is likened to finding a needle in a haystack and technological advances are needed to enable easier detection. Additionally, clinical uptake remains low due to a high false-negative rate and a lack of trust in the technologies.

Join us for Liquid Biopsy ONLINE – a virtual 4-part series where we dive into the technological advances that are driving liquid biopsy development and how we can address the challenges facing clinical uptake.

Webinar Agenda:

Webinar 4: Novel biomarkers and other fluids

Thursday, 30th September - 3pm BST/ 4pm CEST/ 10am EDT

Liquid biopsies tend to measure circulating tumour cells or cell-free DNA in blood, but recently tumour-derived materials have been found in other bodily fluids such as cerebrospinal fluid or urine. This webinar will explore upcoming biomarkers which can be detected in bodily fluids, and other opportunities for detection.

Omics analysis of pancreatic cancer platelets reveals active “education”, and new liquid biopsy sources for cancer detection – Elisa Giovannetti, Principal Investigator & Associate Professor, VU University Medical Center Amsterdam

Application of single cell analysis in cerebrospinal fluid liquid biopsies- Bernhard Polzer, Group Head Of Cellular And Molecular Diagnostics, Fraunhofer ITEM

Liquid biopsy in cancer: the potential of circulating miRNAs – Athina Markou, Assistant Professor of Analytical Chemistry, University of Athens

This webinar has been made possible due to the kind support of our partner Cytiva.

Other webinars in this series:

Webinar 1: Precision medicine in the context of Liquid Biopsy and MRD

Tuesday, 21st September - 3pm BST/ 4pm CEST/ 10am EDT

Liquid biopsies can be utilised in a clinical setting to diagnose cancers, understand molecular drivers of cancer, track minimal residual disease and track treatment-resistant clones.

This webinar will focus on liquid biopsies in the context of precision oncology and how this can inform clinical decision making for improved patient outcomes.

Liquid biopsy for easy and difficult cancers – Tim Aitman, Professor, University of Edinburgh

ctDNA analysis for solid tumor MRD detection – Aadel Chaudhuri, Assistant Professor, Washington University School of Medicine

A personalized approach for MRD detection: the future of recurrent cancer and therapy monitoring - Bob Daber, Chief Scientific Officer, Oncology, Invitae

Webinar 2: Liquid biopsies in clinical trials

Thursday, 23rd September - 3pm BST/ 4pm CEST/ 10am EDT

Liquid biopsies have the potential to impact clinical trials and to prove the clinical utility, more large-scale clinical trials are needed. This webinar highlights some success stories and data from liquid biopsies in clinical trials.

Overview of the solid tumour MRD landscape – Chris Abbosh, Medical Oncology Clinician Scientist, UCL

IMvigor trial – Thomas Powles, Director, Barts Cancer Center

Liquid biopsies for faster diagnosis - Naureen Starling, Principal Investigator, Royal Marsden Hospital

Talk title TBC - Angel Rodriguez, Medical Director, Oncology, Natera

Webinar 3: Moving from research to clinical implementation

Tuesday, 28th September - 3pm BST/ 4pm CEST/ 10am EDT

Clinical uptake of liquid biopsies remains slow due to the high false negative rate and distrust. This webinar will focus on the move from bench to bedside and how we can address the challenges associated with clinical implementation.

Panellists:

Maria Jose Serrano, Associate Professor, University of Granada

Remond Fijneman, Associate Group Leader, Netherlands Cancer Institute

Anca Oniscu, Consultant Pathologist, Royal Infirmary Edinburgh

Angel Rodriguez, Medical Director, Oncology, Natera

Hosted by

  • Team member
    DG T
    Diana Georgi FLG

  • Guest speaker
    BP G
    Bernhard Polzer

  • Guest speaker
    EG G
    Elisa Giovannetti

  • Guest speaker
    EG G
    Elisa Giovannetti

  • Guest speaker
    AM G
    Athina Markou

Front Line Genomics

Delivering the Benefits of Genomics to Patients Faster

Front Line Genomics is a genomics-focused media company, with a social mission to deliver the benefits of genomics to patients faster. We organise the Festival of Genomics, digital events, reports, webinars and digital events, as well as operating a content-rich website.