5D-STEM Mapping of Crystalline Orientation and Mixed Assembly of Gold Nanostructures in Liquid Phase

Abstract: In-situ liquid-phase TEM enables direct visualization of dynamic processes at solid–liquid interfaces but linking morphology to crystallography in liquid remains challenging. In this webinar, I will show how integrating nanochannel liquid cells with 4D-STEM enables mapping of crystalline orientation, long-range ordering, and rotational dynamics of self-assembled gold nanorods in water. Using short-dwell diffraction with a hybrid pixel detector, we capture transient structural events with high spatial and temporal resolution. I’ll conclude by discussing the path toward 5D-STEM, where external stimuli such as light, gas, or heat further expand the experimental landscape to study catalytic, energy, and beam-sensitive biological systems in near-native environments.

Bio: Dr. Pari Moradifar is a Principal Research Staff Scientist at Stanford University. She is an expert in in-situ electron microscopy and multiple modalities of electron spectroscopy. She has pioneered in-situ liquid 4D-STEM (en route to 5D-STEM) experiments using Insight Chips holders and is currently developing new methodologies to understand assembly pathways and mechanisms of gold nanostructures in liquid environments.