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Delmic Cryo-ET Journal Club Series - The Application of In-situ Cryo-ET to Coronavirus Research

About this event

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a pandemic causing over 11 million cases and 500 000 deaths worldwide. The world’s scientists and global health professionals are trying their best to look into coronavirus and develop new standards to contain the spread of the coronavirus pandemic and help those affected. In the second episode of Delmic Cryo-ET Journal Club we will shed some light on the articles about how cryo-electron tomography can be applied to study coronavirus.

Our application specialists Marit Smeets and Caspar Jonker will discuss two new preprints on bioRxiv, in which the structure and replication of coronaviruses are characterized using in-situ cryo-ET in combination with FIB milling. By using this technique the viruses were studied in great detail during infection and based on these results both preprints suggest possible drug targets. During the journal club, we will evaluate the techniques used and the implications of findings in the two preprints.

Join us to discuss how cryo-ET is used in the ongoing coronavirus research! You are welcomed to actively participate in the discussion at the end of the journal club and share your thoughts in the chat box.

We invite you to read the preprints before the journal club to prepare for an interesting discussion:

A molecular pore spans the double membrane of the coronavirus replication organelle 

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

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  • Guest speaker
    G
    Marit Smeets

Delmic

Powerful insights, simple workflows.

Delmic is a passionate high-tech company that develops powerful and user-friendly equipement for light and electron microscopy.
Through our great service, communication and expertise we help researchers and companies to focus on their research, and not on the instrument.