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Cancer Genomics ONLINE - Webinar 2: Insights into clonal evolution and tumour heterogeneity

About this event

The field of cancer genomics is evolving as our sequencing abilities and our technologies improve. With each advancement in tracking the evolution of the cancer genome, and other complexities contributing to disease progression, we expose new tumour vulnerabilities.

Join us for the next series of Cancer Genomics ONLINE as we delve into the single-cell and spatial analyses used to explore the evolving tumour landscape. We uncover the multi-omics research into drug resistance pathways, and new insights into AI in precision oncology. Discover how computational biology can show the interplay between tumours and their environment; and how these analyses could uncover novel therapeutic opportunities.

Webinar 2: Insights into clonal evolution and tumour heterogeneity

Tuesday 18th October 3pm BST/ 4pm CET/ 10am EDT

Tumours are continuously adapting as they are exposed to stressors and treatments. This webinar will explore the role of clonal evolution during tumour growth and metastasis, with a focus on the latest single-cell and spatial analysis in the field. We provide insights into the heterogeneous nature of tumours; into the plasticity exhibited by tumours as they develop; and into how we can take advantage of these pathways to deliver personalised treatments.

Next generation spatial genomic tools for uncovering tumor heterogeneity - Fei Chen, Core Institute Member, Broad Institute of MIT and Harvard

Single-cell multi-omics allows functional characterization of structural variants in leukemia - Jan Korbel, Head of Data Science, EMBL

Webinar 3: Unravelling the genetics of the tumour microenvironment

Tuesday 25th October 3pm BST/ 4pm CET/ 10am EDT

It is well acknowledged that cancer cells interact with their environment in a complex manner. This webinar will provide critical insights into the genetics underlying the tumour microenvironment and its continual crosstalk with cancer cells. We focus on the latest computational biology analysis to understand these tumour ecosystems and how these could be manipulated for therapeutic benefit.

Hunting clones with big data - Sagi Abelson, Principal Investigator, Ontario Institute for Cancer Research

Multi-omics description and network-based modelling of the tumour microenvironment Vera Pancaldi, Senior Researcher, Cancer Research Center of Toulouse

Genomic and digital pathology approaches to elucidate the tumour microenvironment of plastic cells - Maria Secrier, Assistant Professor in Computational Biology, UCL Genetics Institute, University College London

Previous webinars in the series:

Webinar 1: Exploiting the cancer genome and beyond for therapeutic intervention

Tuesday 11th October 3pm BST/ 4pm CET/ 10am EDT

Cancer development is driven by an accumulation of genetic and epigenetic mutations resulting in uncontrolled growth. With metastasis remaining the greatest killer of cancer patients, understanding the inherent tumour biology is vital in accelerating diagnosis, and defining pathways of treatment resistance. This webinar will explore utilising the cancer genome and beyond to treat each tumour individually.

Beyond nucleic acids: adding proteomics and phosphoproteomics to multi-omic studies of drug resistance - Karin Rodland, Director of Precision Medicine Innovation, Pacific Northwest National Laboratory

Detection of mutations in matched FFPE and cfDNA samples - Han Wei, Staff Applications Scientist, Beckman Coulter

Exploiting the cancer epigenome for therapeutic intervention - Kunal Rai, Associate Professor of Genomics Medicine, MD Anderson Cancer Center

Multi-omics and AI for precision oncology - Altuna Akalin, Group Leader, Head of Bioinformatics & Omics Data Science Platform, Max Delbrück Center

Hosted by

  • Guest speaker
    JK G
    Jan Korbel

  • Team member
    CH T
    Celine Hashweh Front Line Genomics

  • Guest speaker
    FC G
    Fei Chen

Front Line Genomics

Delivering the Benefits of Genomics to Patients Faster

Front Line Genomics is a genomics-focused media company, with a social mission to deliver the benefits of genomics to patients faster. We organise the Festival of Genomics, digital events and webinars. We also produce reports and operate a content-rich website.