Single-Cell for Cancer Biology Webinar 2: Single-Cell Tumor Microenvironment Immune Dynamics  

Single-cell analysis has revolutionized our understanding of cancer genomics, developmental biology, and immunology by uncovering the dynamics of tumor heterogeneity, the tumor microenvironment (TME), and immune responses. By using single-cell sequencing, researchers can dissect the cellular composition of tumors with high resolution, revealing diverse cell populations and their interactions. This not only highlights the complexities of cancer progression but also informs the development of novel immunotherapies and personalized treatments.

Join our upcoming Single-Cell for Cancer Biology ONLINE Webinar Series, as we tap into the latest impact that single-cell omics methodologies are having on cancer research. This webinar will:

• Explore single-cell applications in understanding and addressing tumor heterogeneity
• Discuss the interactions between cancer cells and the TME
• Investigate immune cell dynamics to identify potential targets for immunotherapy

Register now to join the virtual series live, with 9 expert talks and live Q&As with the speakers, so you can ask your burning questions to help elevate your research.

**Please note that by registering for one webinar in the series, you will automatically be registered to all subsequent webinars**

Webinar 2: Single-Cell Tumor Microenvironment Immune Dynamics

Thursday 18th April, 2024 at 3pm BST / 4pm CET/ 10am EST

This webinar will cover the latest examples of using single-cell analysis to understand TME dynamics. The speakers will showcase recent advances in identifying different cancer types, identifying novel immune evasion mechanisms all of which reveal novel therapeutic targets for cancer treatment.

Talk 1: Glioblastoma Tumor Microenvironment Linked to Single-Cell Tumor Heterogeneity & Immune Infiltration - Michalina Janiszewska, Assistant Professor, Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

Talk 2: Dissecting Phenotypic Heterogeneity in Colorectal Cancer Metastasis - Mirjana Efremova, Lecturer, Group Leader, Queen Mary University London

Talk 3: Unlocking the Potential of Foundation Models in Single-Cell RNA-Seq to Enhance Insights into Tumor Immunity - Jordan Krull, Post-Doctoral Research Scholar, Pelotonia Institute for Immuno-Oncology, Ohio State University

Sponsored by:

Webinar 3: Single-Cell Omics Methods for Resolving Cancer Cell Heterogeneity

Thursday 25th April, 2024 at 3pm BST / 4pm CET/ 10am EST

This webinar closes of our series by highlighting current advances in studying and analysing tumor heterogeneity using single-cell sequencing. Using epigenomic, metabolomic and spatial data, our speakers will show how exposing multi-omic cellular heterogeneity creates pathways to new biomarkers, drug pathways and, ultimately, treatments.

Talk 1: Single Cell Metabolomics for Breast Cancer to Identify Cancer Subtypes & Subclusters - Annalisa Occhipinti, Associate Professor, Teeside University

Talk 2: Single-Cell Profiling to Decipher Mechanistic Insights of Cell Heterogeneity During [Lung] Cancer Initiation, Metastasis and Treatment - Lindsay LaFave, Assistant Professor, Albert Einstein College of Medicine

Talk 3: Strategies for Successful Single-Cell and Spatial Transcriptomics Experiment Planning - Meryam Beniazza, Single-Cell Multi-omics Specialist, The University of Edinburgh

Previous webinar available on-demand:

Webinar 1: Single-Cell Epigenetic Integration for Exploring Cancer Cell Dynamics

This webinar will cover the uses of single-cell epigenetic technology to understand gene regulatory networks and epigenetic deregulation in cancer biology. It will discuss the computational principles for using single-cell sequencing to understand epigenetics, while also highlighting how single-cell can be used in the context of bulk data.

Talk 1: Single-Sample Network Modelling in Cancer Biology in the Context of Bulk Data - Kimberly Glass, Assistant Professor, Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School

Talk 2: Epigenetic Deregulation in NSCLC Beyond Tumor Cells – Mei-Ju (May) Chen, Senior Post-Doc Bioinformatician, DKFZ Heidelberg

Talk 3: Technology and Computational Tools for scRNA/ATAC-seq Integration of Genetic & Epigenetic Disease Evidence - Judith Zaugg, Group Leader, EMBL Heidelberg