About this event
From cancer prevention to cancer biology, and for both translational and clinical studies, multiomic spatial biology is proving to be an exceptional tool to answer new questions and accelerate results.
In this webinar, the winner of the Spatial Biology EACR & NanoString Grant program, in collaboration with Illumina, will present their cancer research study as they unravel biological complexity in the immune landscape in brain metastasis using spatial technologies.
In situ spatial transcriptomics, powered by GeoMx® Digital Spatial Profiler, allows you to decide where to draw the line in choosing the tissue microenvironments and cell types that matter most for your research projects. Allowing the tissue sample to be the guide means it is possible to gather accurate information about spatial relationships among populations of cells, and ultimately uncover novel and effective clinical treatments.
Are you in search of innovative biomarkers, new drug targets, or distinctive gene and protein signatures?
Join this webinar to:
NanoString spatial biology solutions – discover where biology happens
- Rudy Van Eijsden, NanoString Technologies
- Vivek Kumar Mishra, Illumina
Case study: Exploring the spatial context of tumour microenvironment evolution upon radiotherapy and adenosine blockade in brain metastasis
- Anna Salamero Boix, Georg-Speyer Haus, Frankfurt
Abstract: Brain metastasis is an unmet clinical need in high demand for novel and effective treatments. In preclinical brain metastasis models, we found that combining radiotherapy with adenosine blockade leads to better tumour control. We leveraged the GeoMx® DSP platform to spatially characterize the cellular and molecular dynamics of the murine brain metastasis tumour microenvironment upon radiotherapy and adenosine blockade. We observed treatment-specific alterations in the immune landscape and identified underlying pathways associated with anti-cancer immunity.
Q&A with the speakers.
This webinar has been produced with the kind support of NanoString Technologies and Illumina. You can find out more about the technologies used in the projects presented in this webinar by visiting the NanoString Technologies and Illumina websites.
Front Line Genomics is a genomics-focused media company, with a social mission to deliver the benefits of genomics to patients faster. We organise the Festival of Genomics, digital events and webinars. We also produce reports and operate a content-rich website.
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