Webinar 1: The Latest Innovations for Understanding Epigenetic Heterogeneity and Dynamics

Epigenetic regulation is profoundly complex – varying across cell types, biological contexts, and time. This complexity creates a significant challenge for researchers who are aiming to generate consistent, interpretable data. Yet, it is within this variability that new diagnostic and therapeutic opportunities are emerging.  

How can cutting-edge technologies help us unravel the dynamic, heterogeneous epigenome to reveal disease mechanisms, improve early diagnosis through biomarkers, and identify novel therapeutic targets? 

Register for the upcoming webinar series: Unlocking the Epigenome: Precision Tools for Complex Disease to:

• Discover cutting-edge tools, such as single-cell epigenomics, long-read sequencing and multi-omics approaches, for interrogation of the epigenome at high resolution. 
• Overcome the challenges posed by epigenetic heterogeneity using key bioinformatic and computational tools for faster insights. 
• Gain key biological insights into the epigenetic evolution of cancer, and how this variability is driving progression and resistance. Could the next therapeutic target be hidden in the epigenome? 
• Leverage computational tools to help interpret the scale and complexity of epigenetic data. 

Webinar 1: The Latest Innovations for Understanding Epigenetic Heterogeneity and Dynamics

Thursday 5th June 2025 at 3pm BST / 4pm CEST/ 10am ET

Join us for our first epigenetics webinar of the series, where we will hear about different methodologies and technologies being used by experts in the field to study the heterogenous and dynamic nature of the epigenome.

Talk 1: Mapping the human body methylome and 3D genome, cell by cell 

Jingtian Zhou, Principal Investigator, Arc Institute

Talk 2: Using the 6-base genome to decode health and disease at the single-base resolution

Andrada Tomoni, Product Manager, biomodal

Talk 3: Epigenetic mechanisms underlying metabolic disease  

Zong Wei, Associate Professor of Physiology, Mayo Clinic

Talk 4: DNA methylation patterns associated with cancer risk and aging

Chiara Herzog, King’s Prize Fellow (Junior Group Leader), King’s College London

Webinar 2: Epigenetics Of Cancer: Mechanisms, Models, And Therapeutic Horizons

Thursday 12th June at 3pm BST / 4pm CEST/ 10am ET

This session explores the epigenetic foundations of cancer, examining how epigenetic changes influence tumour behaviour and their role in prognosis and treatment.

Talk 1: The role of Polycomb proteins and 3D genomic architecture in epigenetic inheritance and cancer  

Giacomo Cavalli, Principal Investigator, Centre National de la Recherche Scientifique

Talk 2: Investigating the oncogenic role of histone acetyltransferase fusions in AML  

Alex Radzisheuskaya, Group Leader, The Institute of Cancer Research

Talk 3: Sub-type specific non-coding RNAs that contribute to epigenetic heterogeneity & prognosis in breast cancer  

Sankari Nagarajan, Lecturer in Chromatin Biology, Deputy Director of Manchester Breast Centre, University of Manchester

Webinar 3: Single-Cell Epigenomics: Precision Technologies for Interrogating the Epigenome of Disease

Thursday 19th June at 3pm BST / 4pm CET/ 10am EST

Discover how single-cell epigenomic technologies are enabling deeper insights into the epigenetic changes driving disease.

Talk 1: Using single cell technologies to assess chromatin  

Sebastian Preissl, Professor and Head of Pharmacology & Toxicology, University of Graz

Talk 2: Single cell epigenomics: Computational tools and approaches  

Michael Scherer, Group Leader, Division of Cancer Epigenomics, German Research Cancer Center DKFZ