Front Line Genomics invites you to their event

Multi-Omics ONLINE: Webinar 1 - Omics Analyses in Human Health and Disease

About this event

Nobody can deny that analysing multiple analytes from a sample is the best way to uncover the full biological picture at any moment in time. Whether this is done by sampling and analysing the multi- “omes” at once, or analysing each one in turn and then piecing this back together through data integration, painting this full picture remains an exciting, but challenging field of research.

Join us for our next online series, Multi-Omics ONLINE, where we delve into the ways that researchers are approaching this challenge. In this webinar series, you will find:

  • Talks and Q&A from 10 international speakers from across Australia, Europe, UK and USA
  • Spotlights on a number of tools for multi-omics integration, and single-cell and spatial analysis, directly from the tool developers
  • Case-studies and use cases for multi-omics in informing therapeutic design, understanding disease mechanism and predicting health outcomes

Register now to join the virtual series live, with ten expert talks and live Q&As with the speakers, so you can ask personalised questions around your needs in multi-omics.

**Please note that by registering for one webinar in the series, you will automatically be registered to all subsequent webinars**

Webinar 1: Multi-omics Applications in Human Health and Disease

Tuesday 7th May, 2024 at 3pm BST / 4pm CET/ 10am EDT

Our three-part series begins by covering various applications of multi-omics in health and disease. First, we will explore the value of integrating multi-omics when designing therapeutics and monitoring drug responses. Second, we will hear about the added power of using the combinatorial genetic and epigenetic 6-base genome in disease research. Following this, our third talk details the use of multi-omics in studying cellular communication, which can reveal insights into inflammatory and infectious diseases. The webinar will conclude with a talk that covers profiling RNA-splicing and the challenges of combining long-read sequencing approaches in a single-cell multi-omics setting.

Talk 1. Unravelling Disease Mechanisms: Multi-omics Integration in Therapeutic Design

Raj Sewduth, Research Manager, KU Leuven

Talk 2. Reveal The Power of The 6-base Genome for Transformative Insights into Current and Future States of Disease

Tom Charlesworth, Director, Market Strategy and Corporate Development, biomodal

Talk 3. Creating Biological Interaction Pathways to Understand Cellular Communication

Marton Olbei, Research Associate, Imperial College London

Talk 4. Unravelling the Cell-Type-Specific Impact of Splicing Aberrations with GoT-Splice

Mariela Cortez-Lopes, Postdoctoral Associate, New York Genome Center

Webinar 2: The Single-Cell and Spatial Multi-Omics Toolbox

Tuesday 14th May, 2024 at 3pm BST / 4pm CET/ 10am EDT

The second webinar in this series focusses on updates to multi-omics single-cell and spatial analysis. Shila Ghazanfar, developer of the popular StabMap method, begins proceedings with a review of the latest class of integration methods: single-cell mosaic data integration. Next, the second talk will dive into Giotto Suite, a major update to the open-source Giotto tools that can process, analyse and visualize spatial multi-omics data at all scales and multiple resolutions. Finally, we will hear about the new two-layer DNA seqFISH+ method for mapping thousands of genomic loci and the nascent transcriptome to create a high-resolution view of subcellular components.

Talk 1: Computational Approaches for Single Cell Mosaic Data Integration

Shila Ghazanfar, Lecturer, ARC DECRA Fellow, University of Sydney

Talk 2: Giotto Suite – A Suite of Tools for Spatial Multi-Omics Analyses

Jiaji Chen, PhD Candidate, Dries Lab, Boston University

Talk 3: High-resolution spatial multi-omics reveals cell-type specific nuclear compartments

Yodai Takei, Postdoc, Caltech

Webinar 3: The Latest Multi-Omics Data Integration Strategies

Tuesday 21st May, 2024 at 3pm BST / 4pm CET/ 10am EDT

Integrating the different data modalities creates new challenges for every combination of omics. So, you can never get enough exposure to innovative methods that the community produces to handle specific problems. In this webinar, we conclude with an overview of three new multi-omics integration methods; MixOmics, an R toolkit with over 20 multivariate methodologies, CustOmics, a deep learning-based, oncology-focused method for integrating histology and molecular profiles, and PaCMAP, for integrating multi-omics data to predict health outcomes.

Talk 1: Multi-variate data integration using MixOmics

Kim-Anh Le Cao, Professor in Statistical Genomics, The University of Melbourne

Talk 2: Multimodal CustOmics: A Unified and Interpretable Multi- Task Deep Learning Framework for Multimodal Integrative Data Analysis in Oncology

Hakim Benikrane, PhD student, Centrale Supelec

Talk 3: PaCMAP-Embedded Convolution Neural Network for Multi-Omics Data Integration

Abed Alkhateeb, Assistant Professor of Computer Science, Lakehead University

Hosted by

  • Guest speaker
    MO G
    Marton Olbei

  • Guest speaker
    MC G
    Mariela Cortés López

  • Guest speaker
    RS G
    Raj Sewduth

  • Guest speaker
    TC G
    Tom Charlesworth

  • Team member
    Od T
    Ollie de Jong Front Line Genomics

Front Line Genomics

Delivering the Benefits of Genomics to Patients Faster

Front Line Genomics is a genomics-focused media company, with a social mission to deliver the benefits of genomics to patients faster. We organise the Festival of Genomics, digital events and webinars. We also produce reports and operate a content-rich website.