Single Cells, Infinite Insights: Overcoming Obstacles for Top-Notch Data

From challenges to solutions: Harnessing high-quality data from every cell

In the last few years, single cell approaches have moved into the mainstream, leading to rapid progress in the understanding of complex biological systems. However, these approaches are extremely difficult to perfect. It’s often difficult to derive high quality data, particularly from cell types and tissues that are harder to process.

In this webinar, we will show you every step of a particularly challenging single cell project, including often neglected pilot experiments, taking you from the initial research questions to the final results.

What the webinar will cover

This webinar will present a fascinating, extremely challenging case study that focused on celiac disease (CD), one of the most common auto-immune disorders. Single-cell RNA sequencing can improve our understanding of the human gut function, both in health and across the spectrum of diseases, including CD.

Here you will embark upon a research journey alongside Luigina De Leo, as she navigates through her investigation towards the generation of impactful final data and a successful outcome. Unlike traditional presentations that showcase only polished final results, this webinar will reveal the entire investigative process, including the challenges faced and the strategies employed to overcome them.

In addition, webinar attendees will have the opportunity to engage in discussions, sharing their own experiences and obstacles encountered in single cell sequencing. As a result, this webinar will be informative and interactive, offering a unique blend of scientific learning and collaborative exploration.

What you will learn from this webinar

• How and why reconsidering your options and strategy can help to overcome challenges in single cell RNA sequencing (scRNA-seq).
• Novel approaches towards tissue dissociation when dealing with difficult cell and tissue types.
• Evidence on why it’s important to maintain and capture all cell types.
• Insights into cell specific changes in gene expression, including identification of cell state.
• Approaches for the recognition of new therapeutic targets and biomarkers.
• Discover how technical consultation can guide you towards the right approaches for a successful research project.

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Principal webinar speaker

Luigina De Leo, Research Scientist, Laboratory of Pediatric Gastroenterology, Institute for Maternal and Child Health IRCCS Burlo Garofolo

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This webinar has been produced with the kind support of Singleron Biotechnologies and Macrogen. You can find out more about the technologies outlined in this webinar by visiting the Singleron Biotechnologies and Macrogen websites.